What is the most important information I should know about Rubraca (rucaparib) tablets?
Rubraca may cause serious side effects, including:
Bone marrow problems called Myelodysplastic Syndrome (MDS) or a type of cancer of the blood called Acute Myeloid Leukemia (AML). Some people who have ovarian cancer and who have received previous treatment with chemotherapy or certain other medicines for their cancer have developed MDS or AML during or after treatment with Rubraca (rucaparib) tablets. MDS or AML may lead to death. If you develop MDS or AML, your doctor will stop treatment with Rubraca.
Symptoms of low blood cell counts are common during treatment with Rubraca, but can be a sign of serious problems, including MDS or AML.
Tell your doctor if you have any of the following symptoms during treatment with Rubraca:
- Weight loss
- Frequent infections
- Blood in urine or stool
- Shortness of breath
- Feeling very tired
- Bruising or bleeding more easily
Your doctor will do blood tests to check your blood cell counts:
- Before treatment with Rubraca
- Every month during treatment with Rubraca
- Weekly if you have low blood cell counts for a long time. Your doctor may stop treatment with Rubraca until your blood cell counts improve
What are the possible side effects of Rubraca?
The most common side effects of Rubraca include:
- Stomach-area pain
- Changes in how food tastes
- Decreased appetite
- Shortness of breath
- Decrease in hemoglobin (anemia)
- Low blood cell counts
- Changes in liver or kidney function blood tests
- Increased cholesterol levels
Call your doctor for medical advice about side effects. You may also report side effects to the FDA at 1-800 FDA-1088.
What should I do if I have side effects?Always report side effects to your healthcare team
Your doctor may temporarily stop treatment with Rubraca or change your dose if you have side effects. This may make it easier for you to keep taking Rubraca. Always follow the instructions from your doctor.
Remember to always tell your healthcare team if you think you’re experiencing a side effect. Partnering with your healthcare team is important to help manage side effects.
Write down your experience
You may find it useful to keep a journal about your Rubraca treatment experience. Download or ask your doctor for the Rubraca Patient Journal, or create one of your own.